Name: Angela Gallagher

Theme: Enzymology

OPTION LIST

A	Acid phosphatase	I	Troponin I
B	Alanine aminotransferase (ALT)	J	Troponin T
C	Alkaline phosphatase	K
D	Amylase	L
E	Aspartate aminotransferase (AST)	M
F	Creatine kinase	N
G	γ-Glutamyl transpeptidase (γ-GT)	O
H	Lactate dehydrogenase (LDH)	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 45 year old women presents with vomiting and severe epigastric pain, which radiates to her back and is partially alleviated by sitting forward. Which enzyme is raised on biochemical testing?

2. A blood test is performed on a 52 year old man 8 days after he experienced crushing central chest pain, which radiated to his left arm and neck. The level of which enzyme is important in confirming his diagnosis?

3. An 82 year old women presented with bone pain, history of fractures and bowing of her tibia. Which enzyme is found to be raised on investigation?

4. A 64 year old man who smokes and has a family history of cardiovascular disease has recently been started on atorvastatin. The level of which enzyme is most likely to be raised?

5. A 58 year old, known alcoholic, presents with hepatomegaly on examination. He denies having had a drink for the past 6 months. Which enzyme can be used as a screen for alcohol intake to determine if he is telling the truth?

ANSWERS

1. D

2. H

3. C

4. F

5. G